What is Nucynta ER (Tapentadol )?
Nucynta ER 100mg (Tapentadol ) is an opioid pain medication. An opioid is sometimes called a narcotic. Nucynta is used to treat moderate to severe pain.
The extended-release form of tapentadol (Nucynta ER) is for around-the-clock treatment of pain that is not controlled by other medicines. It is not for use on an as-needed basis for pain.
Nucynta may also be used for purposes not listed in this medication guide
You should not use Nucynta if you have severe breathing problems, or a bowel obstruction called paralytic ileus.
Do not use Nucynta ER 100mg (Tapentadol ) if you have used a MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.
Tapentadol can slow or stop your breathing, especially when you start using this medicine or whenever your dose is changed. Never take this medicine in larger amounts, or for longer than prescribed. Do not crush, break, or open an extended-release tablet. Swallow it whole to avoid exposure to a potentially fatal dose.
Before taking this medicine
You should not use Nucynta if you are allergic to tapentadol, or if you have:
severe asthma or breathing problems; or
a blockage in your digestive tract (stomach or intestines).
Do not use Nucynta ER 100mg (Tapentadol ) if you have taken a MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, and tranylcypromine.
Tapentadol may be habit forming. Never share Nucynta with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. Selling or giving away Nucynta to any other person is against the law
Some medicines can interact with tapentadol and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take medicine for depression, mental illness, Parkinson’s disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.
To make sure this medicine is safe for you, tell your doctor if you have ever had:
- any type of breathing problem or lung disease;
- a head injury, brain tumor, or seizures;
- drug or alcohol addiction, or mental illness;
- urination problems;
- liver or kidney disease; or
- problems with your gallbladder, pancreas, or thyroid.
If you use tapentadol while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether tapentadol passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
Do not give Nucynta to a child.
How should I take Nucynta?
Take Nucynta exactly as prescribed. Follow all directions on your prescription label. Nucynta can slow or stop your breathing, especially when you start using this medicine or whenever your dose is changed. Never take Nucynta in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in relieving your pain.
What should I avoid?
Do not drink alcohol. Dangerous side effects or death could occur when alcohol is combined with tapentadol.
This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how Nucynta will affect you. Dizziness or severe drowsiness can cause falls or other accidents.
Nucynta side effects
Get emergency medical help if you have any of these signs of an allergic reaction to Nucynta: hives, chest pain, fast heartbeats, difficult breathing, swelling of your face, lips, tongue, or throat.
Like other narcotic medicines, Nucynta can slow your breathing. Death may occur if breathing becomes too weak.
Call your doctor at once if you have:
- weak or shallow breathing, weak pulse, slow heartbeat;
- a light-headed feeling, like you might pass out;
- agitation, feeling hot;
- seizure (convulsions);
- severe drowsiness or dizziness, confusion, problems with speech or balance;
- infertility, missed menstrual periods;
- impotence, sexual problems, loss of interest in sex; or
- low cortisol levels – nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.
Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.
Long-term use of opioid medication may affect fertility (ability to have children) in men or women.